Histonemodification相关论文
Acupuncture has been widely used for treating diseases since the ancient days in China,but the mechanism by which acupun......
Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian coun......
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A unique histone H3K4me3 genome binding pattern identified in a cancer pedigree with an MLL3 germlin
Objective Evidence suggests that alterations in histone modifications are crucial in cancer development and progression.......
Background: Higher-order chromatin structure of eukaryotes is a key regulator of gene transcription in a long range[1].B......
Background: Histone modification is one of the key epigenetic regulation mechanisms which plays a critical role in vario......
Background: It is well known that histone modifications can control gene expression, and the data of histone modificatio......
Background: DNA methylation and various types of histone modifications are widely studied epigenetic modifications that ......
Background: The role of miRNA in gene regulatory networks has been becoming more clear.To determine the TF-miRNA regulat......
Introduction: Pain has been the fifth vital sign in clinical care,and pain management is an important need in clinical q......
Histone methylation and acethylation contribute to rifampin-mediated induction of CYP3A4 through the
OBJECTIVE CYP3A4 is one of the major drug-metabolizing enzymes in humans and is responsible for the metabolism of over 5......
HBO1,a member of the MYST family histone acetyltransferases(HATs),is required for global acetylation of H3K14 and embryo......
The N-terminal tails of the nucleosomal core histones are subject to various kinds of post-translational modifications.I......
The prediction of gene expression levels with the histone modifications by the increment of diversit
Background: By studying the correlation of histone modifications and the process of transcription, it has been showed th......
Background: Research on chromatin regulators (CRs) becomes hotspot as the discovery that CRs havc functions on regulatin......
Expression and epigenetic regulation of angiogenesis-related factors during dormancy and the recurre
Background:The initiation of angiogenesis can mark the transition from tumor dormancy to active growth and recurrence.Me......
Histone modifications can include methylation,numerous different acylations,phosphorylation,and glycosylation,among othe......
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The theoretical study of histone modification and its effects on gene expression in the embryonic st
Background: Epigenetic modification plays crucial roles in directing spatial-and temporal-specific gene expression d......
In eukaryotic chromatin, as epigenetic information is encoded and decoded through the combination function of multip......
Histone modifications play important roles in regulating eukaryotic gene expression and have been used to model expr......
Background: In the human genome, alternative splicing is a versatile mechanism to regulat gene expression at the lev......
Enhanced salicylic acid biosynthesis contributes to increased resistance to biotrophic bacterial pat
Heterosis, the phenotypic superiority of a hybrid over its parents, has been demonstrated for many traits in Arabido......
组蛋白修饰与miRNA调控是表观遗传学中的重要组成部分,在细胞生物学过程中发挥着重要的作用,可调控肿瘤的发生、发展.近年来许多研......
衰老作为一种复杂的生命过程，在此过程中有多种因素参与并发挥作用。主要包括体内信号通路中某个因子的基因突变（包括胰岛素信号通路......
目的探讨燃煤型砷中毒人群外周血淋巴细胞组蛋白H3K14乙酰化（H3K14ac）修饰水平与砷中毒及遗传损伤的关系，为燃煤型砷中毒表观遗传调控......
流行病学研究显示,在砷暴露人群中肺癌、膀胱癌和肝癌等发生比例较高.作为弱致突变致癌物,砷诱导肿瘤的发生机制尚未完全阐明.近年......
目的观察饮水砷暴露对人群外周血白细胞中组蛋白H3第4位赖氨酸三甲基化（H3K4me3）和H3第79位赖氨酸三甲基化（H3K79me3）修饰水平的影响，分......
砷的致癌分子机制尚未完全阐明，表观遗传学作用参与了砷诱导肿瘤发生过程。作为一种重要的表观遗传机制，组蛋白修饰在肿瘤发生发展过......
表观遗传学的主要内容是研究在不改变DNA序列的前提下调控遗传物质表达的过程及其机制。表观遗传调控过程十分复杂，主要包括DNA甲基......
表观遗传学是研究转录后与DNA结合的蛋白的修饰,而不是DNA序列的改变.心血管疾病是由环境因素和遗传因素相互作用引发的一种慢性疾......
Hippo pathway can regulate cell division,differentiation and apoptosis,and control the shape and size of organs.To study......
